Native Type II collagen is collagen that retains its natural molecular structure, including structural features of its characteristic triple helix.
Type II collagen is the predominant collagen type in articular cartilage, where it contributes to the structural framework of the cartilage matrix.
When Type II collagen is denatured, its native structure is disrupted. Native, or undenatured, Type II collagen is therefore different from hydrolysed Type II collagen peptides.
This preserved structure is important because native Type II collagen has been investigated for its interaction with the immune system and its potential role in supporting joint health.